Yesterday I took the plunge and upgraded may Acer Aspire One Netbook, which is the AO532-2326 model to Ubuntu 10.10 Maverick Meerkat. I used the update manager to perform the upgrade and every thing went fine. The new Unity desktop is really sharp compared to the desktop that came with Ubuntu Linux 10.04.
The upgrade went fine by opening a terminal and running update-manager -d.
The mousepad still does not quite work right. The mouse stays active while you type, causing inadvertent mouse clicks while typing. To get around this I use the Function-F7 key to enable and disable the mouse whenever I am typing in a window. I do not have this problem if I use the Windows 7 OS that is also installed on this netbook.
Another small change is that you may want to use the new Ubuntu fonts that come with Maverick Meerkat. These can be enabled in the desktop appearances section.